Rubella Diagnostics

Laboratory parameters of the 1st order – obligatory laboratory tests

  • IgM and IgG antibodies – for detection of acute rubella infection.
  • HAH test (hemagglutination inhibition test) > 1:32 – sufficient immunity.

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Isolation of the virus’ from pharyngeal lavage fluid or urine.
  • Tissue biopsies, blood, or cerebrospinal fluid (CSF) can be used to detect rubella antigens
  • Amniotic fluid (amniotic fluid) and fetal blood testing can be performed as prenatal diagnostic tests in cases of questionable or confirmed rubella virus infection.
    Caution.
    If the mother is infected in the 1st trimester, infectivity is already 5-7 days before the onset of exanthema!