Definition A secondary adrenal cortex insufficiency is caused by a deficiency of the hormone ACTH (adrenocorticotropic hormone). This hormone is naturally produced in the pituitary gland and has a stimulating effect on the production of cortisol and the sex hormones, the so-called androgens. Pathological changes in the pituitary gland, also known as the adenohypophysis, can … Secondary adrenocortical insufficiency
The treatment The treatment of secondary adrenal insufficiency is usually with the administration of drugs. The missing cortisol is thus replaced. The dosage of the cortisol is important here; this can change depending on physical condition or performance requirements. In the case of a febrile infection, for example, the body’s cortisol requirement can increase – … The treatment | Secondary adrenocortical insufficiency
Difference to tertiary adrenal cortex insufficiency Tertiary adrenal insufficiency is often described in the literature as a cortisol deficiency that occurs after a dose reduction or sudden cessation of drug-administered cortisol. This sounds a little confusing at first, but can be explained quickly. The cortisol intake tells the body that sufficient cortisol is available. The … Difference to tertiary adrenal cortex insufficiency | Secondary adrenocortical insufficiency
