Erectile Dysfunction: Causes and Treatment

Symptoms Erectile dysfunction or so-called erectile dysfunction refers to the persistent or recurrent inability to achieve or maintain an erection, which is necessary for sexual activity. This makes sexual intercourse impossible and severely limits sexual life. For the affected man, erectile dysfunction can be a great psychological burden. It can trigger stress, negatively affect self-esteem … Erectile Dysfunction: Causes and Treatment

Abiraterone Acetate

Products Abiraterone is commercially available in the form of film-coated tablets (Zytiga). It has been approved in many countries since 2011. Structure and properties Abiraterone acetate (C26H33NO2, Mr = 391.5 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug and is rapidly biotransformed in the body to … Abiraterone Acetate

Antiandrogens

Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens

Darolutamide

Products Darolutamide was approved in the US in 2019 and in the EU and Switzerland in 2020 in film-coated tablet form (Nubeqa). Structure and properties Darolutamide (C19H19ClN6O2, Mr = 398.8 g/mol) exists as a white to grayish or yellowish-white crystalline powder and is practically insoluble in water. The drug has a nonsteroidal structure and is … Darolutamide

Apalutamide

Products Apalutamide was approved in the US and EU in 2018 and in many countries in 2019 in film-coated tablet form (Erleada). Structure and properties Apalutamide (C21H15F4N5O2S, Mr = 477.4 g/mol) exists as a white to slightly yellow powder that is practically insoluble in water. The active metabolite -demethylapalutamide is also active, but more weakly … Apalutamide

Osaterone Acetate

Products Osaterone acetate is commercially available in tablet form as a veterinary drug. It has been approved in many countries since 2008. Structure and properties Osaterone acetate (C22H27ClO5, Mr = 406.9 g/mol) Effects Osaterone acetate (ATCvet QG04CX90) has antiandrogenic properties. Indications Treatment of benign prostatic hyperplasia in male dogs.

Androgens: Steroid Hormones

Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones

Androgenetic Alopecia in Women

Symptoms Increasing diffuse thinning of the hair occurs in the area of the middle parting. In this case, unlike androgenetic alopecia in men, not all hair is lost, but the scalp becomes visible over time. Often, a densely hairy strip remains frontally above the forehead. Dense hair is also still found on the sides and … Androgenetic Alopecia in Women

Antiandrogens: Effect, Uses & Risks

The antiandrogens are used as an active ingredient against the male sex drive. In contrast, however, the application is equally possible in women. In addition to treating acute symptoms, long-term use can cause permanent effects and side effects. What is antiandrogens? The antiandrogens are used as an active ingredient against the male sex drive. In … Antiandrogens: Effect, Uses & Risks

Anaphrodisiacs

Active ingredients Antiandrogens: Cyproterone acetate Traditional: monk’s pepper

Drospirenone

Products Drospirenone is commercially available as a fixed combination with ethinyl estradiol for contraception in the form of film-coated tablets (Yasmin, Yasminelle, YAZ, generics, auto-generics). Drospirenone is also used in combination with estradiol for hormone replacement therapy (Angeliq). Bayer’s originals Yasmin, Yasminelle and YAZ will go off the market in many countries in December 2021. … Drospirenone