Products Bicalutamide is commercially available in the form of film-coated tablets (Casodex, generics). It has been approved in many countries since 1995. Structure and properties Bicalutamide (C18H14F4N2O4S, Mr = 430.37 g/mol) is a racemate, with the -enantiomer being almost exclusively responsible for the antiandrogenic effect. It exists as a white powder that is practically insoluble … Bicalutamide
Products Enzalutamide was initially registered in capsule form (Xtandi). Film-coated tablets were approved in many countries in 2019. They are smaller and therefore easier to take. Enzalutamide was approved in the United States in 2012 and in many countries and the EU in 2013. Structure and properties Enzalutamide (C21H16F4N4O2S, Mr = 464.4 g/mol) is an … Enzalutamide
Products Flutamide was approved in many countries in 1984 in tablet form (Flucinom, 250 mg) and is no longer registered. It can be replaced by modern antiandrogens if needed or imported from abroad. Structure and properties Flutamide (C11H11F3N2O3, Mr = 276.2 g/mol) exists as a pale yellow crystalline powder that is practically insoluble in water. … Flutamide
Products Extracts from the fruits of saw palmetto are commercially available in many countries, mainly in the form of capsules. The medicinal drug is available in pharmacies and drugstores, but is rarely used. Stem plant The saw palmetto, a member of the palm family, is a small palm tree that grows to a maximum height … Saw Palmetto
Products Dienogest is commercially available in many countries as a fixed combination with estradiol valerate in tablet form (Qlaira). Furthermore, a monopreparation for endometriosis therapy is available (Visanne, see under Dienogest Endometriosis). The fixed combination with ethinyl estradiol (Valette, generic) was approved in many countries in 2014. Dienogest + estradiol Qlaira has been on the … Dienogest
Products Cyproterone acetate is commercially available in the form of dragées in combination with ethinyl estradiol (generics). The drug has been approved in many countries since 1987. This article refers to the original Diane-35 and corresponding generics. Other drugs containing cyproterone acetate are available for other indications. Bayer’s original Diane-35 goes off the market in … Cyproterone Acetate
Products Spironolactone is commercially available in film-coated tablet form as a monopreparation (Aldactone) and in fixed combination with furosemide (Furospir). It was developed in the 1950s at G.D. Searle in Chicago and approved in 1959, and in many countries in 1961. Structure and properties Spironolactone (C24H32O4S, Mr = 416.6 g/mol) exists as a white to … Spironolactone
Background The tear film is the outermost connection between the surface of the eye and the environment and is involved in the visual process. It moisturizes, protects and nourishes the eye. It is an aqueous gel containing water, mucins, salts, antibacterial proteins and antibodies, vitamin A, and lipids, among other substances, and is distributed over … Dry Eyes: Causes and Remedies
Symptoms Dry skin is rough, dull, scaly, brittle, pale and less supple than normal skin. It may feel tight, painful, and irritated. Dry skin is a risk factor for the development of inflammatory, allergic and infectious skin diseases and is often accompanied by inflammation, tearing, bleeding and itching. It occurs mainly on the extremities and … Dry Skin: Causes and Remedies
Products Oral contraceptives are commercially available in the form of film-coated tablets and coated tablets. Numerous products with different active ingredients are available from different manufacturers. Structure and properties Oral contraceptives usually contain an estrogen (mainly ethinyl estradiol, sometimes estradiol) and a progestin. Preparations are also available that contain only a progestin (minipill, e.g., desogestrel, … Oral Contraceptives
Definition Increased body and facial hair in women corresponding to the male hair type due to androgen-induced conversion of vellus hair to terminal hair. Symptoms Excessive and altered hair growth (thick and pigmented) on the face, chest, abdomen, legs, buttocks, and back Acne Deeper voice Increased muscle mass Decrease in breast size Androgenetic alopecia Views … Hirsutism: Excessive Hair Growth
Products Chlormadinone acetate is commercially available in tablet form in combination with ethinyl estradiol (Belara, Ladonna, Belarina, generics). It has been approved in many countries since 2001. Structure and properties Chlormadinone acetate (C23H29ClO4, Mr = 404.9 g/mol) Effects Chlormadinone acetate (ATC G03DB06) has antiandrogenic properties. Indications In combination with ethinyl estradiol: hormonal contraception.
