Active ingredients Nonsteroidal estrogen antagonists (SERMs). Tamoxifen (Nolvadex, generic). Toremifene (Fareston, off label). Clomiphene (Serophene, out of trade). Steroids: Fulvestrant (Faslodex) Indications Mammary carcinoma (breast cancer) Ovarian stimulation
Products Clomiphene was commercially available in tablet form (Serophene, Clomid). It was approved in many countries since 1967 and is currently no longer available. Drugs containing the active ingredient can be imported from abroad. Structure and properties Clomiphene (C26H28ClNO, Mr = 405.95 g/mol) is a nonsteroidal triphenylethylene derivative that exists as an unequal mixture of … Citalopram: Drug Effects, Side Effects, Dosage and Uses
Products Tamoxifen is commercially available in the form of film-coated tablets (Nolvadex, generic). It was synthesized in 1962 and tested as a contraceptive (“morning-after pill”) but was not suitable for this purpose. It was first used as a breast cancer drug in the early 1970s. It has been approved in many countries since 1976. Structure … Tamoxifen (Nolvadex): Drug Effects, Side Effects, Dosage and Uses
Definition There are many ways to fight a tumor disease, one of them is hormone therapy. Breast cancer is often associated with hormones, so that hormone therapy can be used to influence the hormone balance. Among other things, this can result in slower growth. Forms of hormone therapy These are the different types of hormone … Hormone therapy for breast cancer
Why is hormone therapy also useful after breast cancer? In tumors that have hormone receptors, the estrogen produced by the body leads to faster tumor growth. In order to prevent or slow down the growth, it is therefore necessary either to stop the hormone production (by radiation or removal of the ovaries) or to prevent … Why is hormone therapy also useful after breast cancer? | Hormone therapy for breast cancer
What are the side effects of hormone therapy? Depending on the active ingredient, various side effects may occur. Antiestrogens such as tamoxifen or fulvestrant typically cause menopausal symptoms because they suppress the effect of the estrogen. These include: In addition, the lack of effect of the estrogen can lead to increased growth of the lining … What are the side effects of hormone therapy? | Hormone therapy for breast cancer
Disadvantages of hormone therapy Hormone therapy has some disadvantages. These include, for example, the very long duration of treatment. As a rule, anti-hormonal therapies must be maintained for 5 to 10 years. This is due to the low aggressiveness of this form of treatment. Another disadvantage of hormone therapy can be temporary menopausal symptoms. Duration … Disadvantages of hormone therapy | Hormone therapy for breast cancer
