Products Direct antiviralia are commercially available as drugs in the form of tablets, capsules, solutions, and creams, among others. The first antiviral agent was approved in the 1960s (idoxuridine). Structure and properties Antivirala are a large group of drugs and have no uniform chemical structure. However, groups can be formed, such as the nucleoside analogs. … Antiviralia
Products Nusinersen was approved in the United States in 2016 and in many countries and the EU in 2017 as a solution for intrathecal injection by lumbar puncture and as the first drug for SMA treatment (Spinraza). Structure and properties Nusinersen is a modified antisense oligonucleotide. Effects Nusinersen (ATC M09AX07) increases the formation of the … Nusinersen
Products Eteplirsen (Sarepta Therapeutics Inc) was approved in the United States in 2016 (Exondys 51). Structure and properties Eteplirsen (C364H569N177O122P30, Mr = 10305.7 g/mol) is a phosphorodiamidate morpholino oligomer (PMO) that binds selectively to exon 51 of pre-mRNA. It is an antisense oligomer with a high molecular weight. The sequence is complementary to the segment … Eteplirsen
