Clobazam: Effects and Side Effects

How does clobazam work? Clobazam is an active substance from the benzodiazepine group. These substances increase the affinity of the body’s own neurotransmitter GABA (gamma-aminobutyric acid) to its binding site on the GABAA receptor. In the presence of clobazam, the GABA effect on the receptor increases. More chloride ions flow into the nerve cell, making … Clobazam: Effects and Side Effects

Benzodiazepines Effects and Side Effects

Products Benzodiazepines are commercially available in the form of tablets, melting tablets, capsules, drops, and injectables, among others (selection). Chlordiazepoxide (Librium), the first benzodiazepine, was synthesized in the 1950s by Leo Sternbach at Hoffmann-La Roche and was launched in 1960. The second active ingredient, the well-known diazepam (Valium), was launched in 1962. Numerous other drugs … Benzodiazepines Effects and Side Effects

Anxiolytics

Products Anxiolytics are commercially available in the form of tablets, capsules, and injectable preparations, among others. Structure and properties Anxiolytics are a structurally heterogeneous group. However, the representatives can be divided into different classes. These include, for example, the benzodiazepines or the tricyclic antidepressants. Effects Anxiolytics have antianxiety (anxiolytic) properties. They usually have additional effects, … Anxiolytics

Clobazam

Products Clobazam is commercially available in tablet form (Urbanyl). It has been approved in many countries since 1979. Structure and properties Clobazam (C16H13ClN2O2, Mr = 300.7 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It belongs structurally to the 1,5-benzodiazepines. The other active ingredients are 1,4-benzodiazepines. Effects Clobazam (ATC N05BA09) … Clobazam