Benzodiazepines

Oxazepam: Drug Effects, Side Effects, Dosage and Uses

Products Oxazepam is commercially available in tablet form (Seresta, Anxiolit). It has been approved in many countries since 1966. Structure and properties Oxazepam (C15H11ClN2O2, Mr = 286.7 g/mol) is a racemate. It exists as a white crystalline powder that is practically insoluble in water. Effects Oxazepam (ATC N05BA04) has antianxiety, sedative, sleep-inducing, anticonvulsant, and muscle … Oxazepam: Drug Effects, Side Effects, Dosage and Uses

Prazepam

Products Prazepam is commercially available in tablet form (Demetrin). It has been approved in many countries since 1977. Structure and properties Prazepam (C19H17ClN2O, Mr = 324.8 g/mol) exists as a white crystalline powder that is practically insoluble in water. It carries a cyclopropyl group. Effects Prazepam (ATC N05BA11) has antianxiety, sedative, relaxant, and depressant properties. … Prazepam

Ketazolam

Products Ketazolam is commercially available in capsule form (Solatran). It has been approved in many countries since 1980. Structure and properties Ketazolam (C20H17ClN2O3, Mr = 368.8 g/mol) structurally belongs to the 1,4-benzodiazepines. Effects Ketazolam (ATC N05BA10) has antianxiety, depressant, muscle relaxant, and anticonvulsant properties. The effects are due to binding to GABA-A receptors and enhancement … Ketazolam

Bromazepam

Products Bromazepam is commercially available in tablet form (Lexotanil). It has been approved in many countries since 1974. Structure and properties Bromazepam (C14H10BrN3O, Mr = 316.2 g/mol) exists as a white to yellowish crystalline powder that is practically insoluble in water. It is a brominated 1,4-benzodiazepine. Effects Bromazepam (ATC N05BA08) has antianxiety, sedative, and depressant … Bromazepam

Clonazepam

Products Clonazepam is commercially available as tablets, injectable solution, and oral drops (Rivotril). It has been approved in many countries since 1973. In the United States, it is marketed as Klonopin. Structure and properties Clonazepam (C15H10ClN3O3, Mr = 315.7 g/mol) exists as a faint yellowish crystalline powder that is practically insoluble in water. It is … Clonazepam

Clorazepate

Products Clorazepate is commercially available in the form of capsules and tablets (Tranxilium, generics). It has been approved in many countries since 1971. Structure and properties Clorazepate is present in drugs as dipotassium clorazepate (C16H11ClK2N2O4, Mr = 408.9 g/mol) is present, a white to pale yellow powder that is slightly to very slightly soluble in … Clorazepate

Temazepam

Products Temazepam is commercially available in capsule form (Normison). It has been approved in many countries since 1983. Structure and properties Temazepam (C16H13ClN2O2, Mr = 300.7 g/mol) is a white crystalline powder that is practically insoluble in water. It is present in drugs as a racemate (hydroxyl group). Temazepam belongs to the 5-aryl-1,4-benzodiazepines. Effects Temazepam … Temazepam

Halazepam

Products Halazepam is commercially available in Portugal (Pacinone tablets) and elsewhere. The original trade name is paxipam. No drugs containing the active ingredient are currently registered in many countries, in Germany, or in the United States. Structure and properties Halazepam (C17H12ClF3N2O, Mr = 352.7 g/mol) is structurally closely related to diazepam (Valium). It exists as … Halazepam

Nitrazepam

Products Nitrazepam is commercially available in tablet form (Mogadon). It has been approved in many countries since 1965. Structure and properties Nitrazepam (C15H11N3O3, Mr = 281.3 g/mol) is a nitrated 1,4-benzodiazepine. It exists as a yellow crystalline powder that is practically insoluble in water. Nitrazepam is structurally closely related to flunitrazepam (Rohypnol). Effects Nitrazepam (ATC … Nitrazepam

Triazolam

Products Triazolam is commercially available in tablet form (Halcion). It has been approved in many countries since 1978. Structure and properties Triazolam (C17H12Cl2N4, Mr = 343.2 g/mol) exists as a white crystalline powder that is poorly soluble in water. It is a triazole derivative (triazol-am). Effects Triazolam (ATC N05CD05) has sedative, antianxiety, anticonvulsant, amnesic, and … Triazolam

Medazepam

Products Medazepam is commercially available in Germany in tablet form (Rudotel). The active ingredient is not registered in many countries. Structure and properties Medazepam (C16H15ClN2, Mr = 270.8 g/mol) is a 1,4-benzodiazepine derivative. Effects Medazepam (ATC N05BA03) has sedative, antianxiety, sleep-inducing, anticonvulsant, and muscle relaxant properties. The effects are due to enhancement of GABAergic transmission. … Medazepam

Lorazepam

Products Lorazepam is commercially available as tablets, meltable tablets, and a solution for injection. In addition to the original Temesta, generics and a combination product with the sedative antihistamine diphenhydramine are also available (Somnium). Lorazepam has been approved in many countries since 1973. Structure and properties Lorazepam (C15H10Cl2N2O2, Mr = 321.2 g/mol) is a white … Lorazepam