De-Grouchy syndrome is a malformation complex of which several subtypes exist. The multiple malformations are caused by deletions on chromosome 18. Patients are treated symptomatically only. What is de Grouchy syndrome? The so-called malformation syndromes are a group of disorders that manifest as a complex of different malformations. One subset of this group of disorders … De Grouchy Syndrome: Causes, Symptoms & Treatment
Holoprosencephaly is a malformation of the human brain that occurs with relatively high frequency. A large proportion of affected embryos die in the womb. Therefore, only a few patients with holoprosencephaly are born alive. Holoprosencephaly forms prenatally and primarily affects the face and the frontal area of the brain. What is holoprosencephaly? Holoprosencephaly is relatively … Holoprosencephaly: Causes, Symptoms & Treatment
Hypertelorism is an abnormally large distance between the eyes that does not necessarily have pathological value. When the phenomenon is present in the context of malformation syndromes, it has pathologic significance and is usually due to a genetic mutation. Treatment of hypertelorism is usually not indicated, but may improve the quality of life of the … Hypertelorism: Causes, Treatment & Help
Four-finger furrow is a hand line of the palm that often occurs in individuals with some form of trisomy. The presence of a four-finger furrow has no pathologic value in and of itself, as the hand line does not affect hand function. For this reason, four-finger furrows do not require specific treatment in either healthy … Four Finger Furrow: Causes, Symptoms & Treatment
