Antiandrogens

Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens

Enzalutamide

Products Enzalutamide was initially registered in capsule form (Xtandi). Film-coated tablets were approved in many countries in 2019. They are smaller and therefore easier to take. Enzalutamide was approved in the United States in 2012 and in many countries and the EU in 2013. Structure and properties Enzalutamide (C21H16F4N4O2S, Mr = 464.4 g/mol) is an … Enzalutamide

Butylhydroxyanisole

Products Butylated hydroxyanisole is found in numerous drugs as an excipient, for example in semisolid and liquid dosage forms, as well as in tablets and soft capsules. Structure and properties Butylated hydroxyanisole (C11H16O2, Mr = 180.3 g/mol) exists as a white to yellowish or faintly pinkish crystalline powder that is practically insoluble in water. It … Butylhydroxyanisole