How Exemestane works Exemestane is an irreversible aromatase inhibitor and as such suppresses the formation of female sex hormones (estrogens). Estrogens (estrone, estradiol, and estriol) are female sex hormones. They are formed in the female body (in small quantities also in the male) from precursor substances, mainly in the ovaries. The sex hormones are important … Exemestane: effects, areas of application, side effects
Products Exemestane is commercially available in the form of dragées and film-coated tablets (Aromasin, generics). It has been approved in many countries since 1999. Structure and properties Exemestane (C20H24O2, Mr = 296.4 g/mol), unlike other aromatase inhibitors, has a steroidal structure and resembles the natural substrate androstenedione. It exists as a white to slightly yellowish … Exemestane
Products Doping agents include approved drugs, legal and illegal intoxicants, experimental agents, and illegally manufactured and trafficked substances. Doping includes non-drug doping methods, such as blood doping, in addition to drugs. Effects Doping agents differ in their pharmacological activities. Stimulants, for example, stimulate and thus increase alertness and aggressiveness for competition. In contrast, beta-blockers provide … Doping in Competitive Sports
Products Aromatase inhibitors are commercially available in the form of film-coated tablets and coated tablets. The first third-generation agent to be approved in many countries was anastrozole in 1996 (Arimidex, USA 1995). Other drugs are available today. The active ingredients available today all belong to the third generation. Earlier agents such as aminoglutethimide and formestane … Aromatase Inhibitors
