Synonyms Haemophilia, inherited bleeding disorder, blood clotting factor deficiency, factor VIII deficiency, factor IX deficiency, haemophiliacs Definition Haemophilia is a hereditary disease of the blood coagulation system: affected patients have impaired blood coagulation, which is manifested by bleeding in the smallest traumas and bleeding is difficult to stop. Coagulation factors cannot be activated, so that … Hemophilia
Diagnosis After asking the patient’s medical history and a thorough physical examination, further steps in the diagnosis of hemophilia follow: In 2/3 of the cases there are cases of haemophilia in the family, which is why it is necessary to ask about a family history of the disease when the patient presents himself to the … Diagnosis | Hemophilia
Complications The substitution of coagulation factors can lead to the formation of antibodies against these factors, so that the substitution in a constant dose no longer has any therapeutic effects. Depending on the determination of the concentration of antibodies in the patient’s blood, a high-dose administration of factor VIII can be carried out with the … Complications | Hemophilia
