How molsidomine works Molsidomine is a drug from the group of vasodilators. The active ingredient has vasodilatory and blood pressure-lowering properties. In coronary artery disease (CAD), the coronary vessels are narrowed, usually due to arteriosclerosis (“hardening of the arteries”). The coronary vessels supply the heart muscle cells with oxygen and nutrients. Later, when the coronary … Molsidomine: Effects, applications, side effects
Products Molsidomine is commercially available in the form of tablets and sustained-release tablets (Corvaton). The drug has been approved in many countries since 1980. Structure and properties Molsidomine (C9H14N4O4, Mr = 242.2 g/mol) is a prodrug that is biotransformed in the liver to the active metabolite linsidomine (SIN-1). It exists as a white crystalline powder … Molsidomin
Products Phosphodiesterase-5 inhibitors are commercially available in the form of film-coated tablets and meltable tablets. Sildenafil (Viagra) was the first active ingredient from this group to be approved in the United States, the EU, and many countries in 1998. Generics are also available today. Sildenafil was originally to be developed by Pfizer for the treatment … Phosphodiesterase-5 Inhibitors
Background Phenylalanine is an essential amino acid that is not produced by the human organism itself. Phenylalanine ingested with food is produced by the enzyme phenylalanine hydroxylase and its cofactor 6-tetrahydrobiopterin (6-BH4) metabolized to tyrosine. Phenylketonuria is an autosomal recessive disorder caused by insufficient activity of phenylalanine hydroxylase, resulting in elevated blood phenylalanine levels, i.e., … Sapropterin
