NSCLC: Description Physicians know several types of lung cancer (mediz. bronchial carcinoma). First, they distinguish two major groups: Non-small cell bronchial carcinoma (NSCLC) and small cell bronchial carcinoma (SCLC). In small cell lung cancer, many small, densely packed cells are found under the microscope. In contrast, the cells in NSCLC are larger. Small cell and … NSCLC: Development, Types, Therapy
Products Gefitinib is commercially available in the form of film-coated tablets (Iressa). It was approved in many countries in 2011. Structure Gefitinib (C22H24ClFN4O3, Mr = 446.9 g/mol) is a morpholine and aniline quinazoline derivative. It exists as a white powder that is sparingly soluble in water, especially at high pH. Effects Gefitinib (ATC L01XE02) is … Gefitinib
Products Docetaxel is commercially available as an infusion preparation (Taxotere, generics). It was approved in many countries in 1996 as a second taxane after paclitaxel (Taxol). Structure and properties Docetaxel (C43H53NO14, Mr = 807.9 g/mol) is present in the drug as docetaxel trihydrate, a white powder that is practically insoluble in water. The lipophilic drug … Docetaxel
Products Paclitaxel is commercially available as an infusion concentrate (Taxol, generic). It has been approved in many countries since 1993. The active ingredient itself is also known as taxol. Protein-bound nab-paclitaxel (Abraxane) was approved in many countries in 2014. Structure and properties Paclitaxel (C47H51NO14, Mr = 853.9 g/mol) is a complex tetracyclic diterpene. It exists … Paclitaxel
The diagnosis of cancer confronts many patients with the question of life and survival. The question “how long do I have left?” burns very quickly under the nails of most of those affected, since the diagnosis “cancer” is still associated with certain death. However, nowadays only a few types of cancer mean certain non-survival. The … Lung Cancer Prognosis
Tumor stage and spread Tumors tend to spread and form further metastases. They spread to the surrounding lymph nodes or via the blood to distant organs. In patients with lung cancer, metastases are mainly found in the surrounding lymph nodes of the thorax as well as in the liver, brain, adrenal glands and skeleton, especially … Tumor stage and spread | Lung Cancer Prognosis
Age and gender The age and gender as well as the general physical and mental condition of the affected person also play a role in the probability of survival. Women have a higher survival rate after 5 years than men. Patients in poor general physical condition are often unable to derive a positive effect from … Age and gender | Lung Cancer Prognosis
