Products Gefitinib is commercially available in the form of film-coated tablets (Iressa). It was approved in many countries in 2011. Structure Gefitinib (C22H24ClFN4O3, Mr = 446.9 g/mol) is a morpholine and aniline quinazoline derivative. It exists as a white powder that is sparingly soluble in water, especially at high pH. Effects Gefitinib (ATC L01XE02) is … Gefitinib
Products Erlotinib is commercially available in the form of film-coated tablets (Tarceva). It has been approved in many countries since 2005. Generic versions were registered in 2018. Structure and properties Erlotinib (C22H23N3O4, Mr = 393.4 g/mol) is present in drugs as erlotinib hydrochloride, a white powder that is sparingly soluble in water. Solubility increases with … Erlotinib
Products Afatinib was approved in the US and EU in 2013 and in many countries in 2014 in film-coated tablet form (Giotrif). Structure and properties Afatinib (C24H25ClFN5O3, Mr = 485.9 g/mol) is a 4-aniline quinazoline derivative that is present in drugs as afatinib dimaleate, a white to brownish-yellow powder that is soluble in water. It … Afatinib
