Introduction – What is Ciclosporin A? Ciclosporin A is an immunosuppressive agent, i.e. a substance that suppresses the immune system and thus downregulates an immune response. For example, Ciclosporin A can be used after transplantation of different organs to prevent the body’s immune system from attacking the foreign organ (transplant). Ciclosporin A is also used … Ciclosporin A
Active ingredient and effect Ciclosporin A is an active ingredient of the immunosuppressive group. By means of a complex mechanism of action, Ciclosporin prevents the formation of so-called cytokines (proteins required for an immune reaction in the body). In addition, Ciclosporin A has an effect on lymphocytes, an important group of cells that are also … Active ingredient and effect | Ciclosporin A
Eye drops with Ciclosporin A Eye drops with Ciclosporin A are used for severe inflammation of the eyes. Ciclosporin reduces the immune response in the eye, producing fewer inflammatory substances and thus reducing potential eye damage. For particularly severe inflammation of the cornea with dry eyes, these eye drops are considered the first choice. Ciclosporin … Eye drops with Ciclosporin A | Ciclosporin A
How much does Ciclosporin A cost? In most cases, the costs for a therapy with Ciclosporin A are covered by health insurance or private health insurance. The drug should only be used if there is a medical indication, in which case the health insurance companies are obliged to pay the costs. Depending on the dosage … How much does Ciclosporin A cost? | Ciclosporin A
Introduction The immune system is the barrier that protects the body from the penetration of pathogens. It consists of a cellular and a so-called humoral part. Cellular components are for example the macrophages (“scavenger cells”), the natural killer cells and the lymphocytes. The humoral part, i.e. the part that is not made up of cells, … Immunosuppressive drugs
Which drugs belong to the immunosuppressive drugs? Many different substances can be summarized under the term immunosuppressants. They act via different mechanisms on the different components of the immune system and are therefore divided into different groups. Probably the most frequently used group are the glucocorticoids. Furthermore, calcineurin inhibitors and mTOR inhibitors are used as … Which drugs belong to the immunosuppressive drugs? | Immunosuppressive drugs
How do immunosuppressants work? Each group of immunosuppressive drugs unfolds its efficacy in a different way. The glucocorticoids unfold their effect by binding via a receptor (NF-kB) located in the cell, which prevents the reading of DNA. As a result, pro-inflammatory proteins and messenger substances of the inflammatory reaction or the immune response can no … How do immunosuppressants work? | Immunosuppressive drugs
What should be considered when discontinuing immunosuppressive drugs? Immunosuppressive drugs are often taken over very long periods of time. Organ transplanted patients must take immunosuppressive drugs throughout their lives to avoid rejection after years. Due to the severe side effects of immunosuppressive drugs, many patients are unwilling to take the medication. In the worst case, … What should be considered when discontinuing immunosuppressive drugs? | Immunosuppressive drugs
Immunosuppressants for the treatment of Crohn’s disease Crohn’s disease is a chronic inflammatory disease that can affect the entire gastrointestinal tract. The following immunosuppressive drugs are used to treat an acute attack: Budesonide, mesalazine and possibly prednisolone. Budesonide is a glucocorticoid that is metabolised to a large extent in the liver. It therefore has mainly … Immunosuppressants for the treatment of Crohn’s disease | Immunosuppressive drugs
Immunosuppressive drugs for the treatment of multiple sclerosis Multiple sclerosis is an inflammatory, autoimmune nerve disease in the course of which the protective layer around the nerve fibers (myelin layer) is increasingly destroyed. MS progresses in phases, i.e. intervals of almost complete freedom from pain alternate with strong attacks of the disease. Especially during the … Immunosuppressive drugs for the treatment of multiple sclerosis | Immunosuppressive drugs
