Quinagolide

Products Quinagolide is commercially available in tablet form (Norprolac). It has been approved in many countries since 1994. Structure and properties Quinagolide (C20H33N3O3S, Mr = 395.56 g/mol) is a non-ergoline dopamine agonist with a similar structure to apomorphine. It is present in drugs as quinagolide hydrochloride. Effects Quinagolide (ATC G02CB04) has dopaminergic properties and inhibits … Quinagolide

Dopamine Agonists

Products Dopamine agonists are commercially available in the form of tablets, sustained-release tablets, transdermal patches, and injectables, among others. Structure and properties The first active ingredients, such as bromocriptine (Figure), were derived from ergot alkaloids. These are referred to as ergoline dopamine agonists. Later, agents with a nonergoline structure, such as pramipexole, were also developed. … Dopamine Agonists

Prolactinomas

Symptoms Symptoms depend on sex, age, adenoma size, and prolactin levels. In women, prolactinoma manifests as menstrual irregularities (absence or delay of periods), infertility, and lactation. In men, it results in testosterone deficiency, reduced libido, erectile dysfunction, impotence, decreased beard growth, and rarely breast pain and lactation. In children, puberty is additionally delayed. In a … Prolactinomas