Products and withdrawal from the market Sibutramine was approved in 1999 and was commercially available in many countries in 10- and 15-mg capsule form (Reductil, Abbott AG). On March 29, 2010, Abbott AG, in consultation with Swissmedic, informed the public that the marketing authorization had been suspended. Since then, sibutramine may no longer be prescribed … Sibutramine
Effects Antiadiposita differ in their effects. They inhibit appetite or increase satiety, reduce the absorption of food components in the intestine or promote their utilization, increase energy metabolism and degrading metabolic processes. The ideal slimming agent would enable rapid, high and stable weight loss and at the same time be very well tolerated and applicable … Slimming Products
Products Tramadol is commercially available in the form of tablets, capsules, melting tablets, drops, effervescent tablets, suppositories, and as a solution for injection. (Tramal, generic). Fixed combinations with acetaminophen are also available (Zaldiar, generic). Tramadol was developed by Grünenthal in Germany in 1962 and has been approved in many countries since 1977 and in the … Tramadol: Drug Effects, Side Effects, Dosage and Uses
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Symptoms Fibromyalgia is a chronic, noninflammatory disorder that manifests as pain throughout the body and is characterized by numerous other complaints. It is much more common in women than in men and usually first appears in middle age. Chronic, bilateral, diffuse pain. Muscle pain, pain in the limbs, back pain, joint pain, neck pain, headaches, … Fibromyalgia Causes and Treatment
Products Venlafaxine is commercially available in tablet and sustained-release capsule form. In addition to the original Efexor ER (USA: Effexor XR), generic versions are also available. The active ingredient was approved in many countries in 1997. Structure and properties Venlafaxine (C17H27NO2, Mr= 277.4 g/mol) is a bicyclic phenylethylamine and cyclohexanol derivative that is structurally closely … Venlafaxine: Drug Effects, Side Effects, Dosage and Uses
Physiological background Sweat is produced by millions of eccrine sweat glands that are distributed throughout the body and are particularly numerous on the palms and soles of the hands, face, and armpits. The eccrine sweat glands are spiral and clustered glands that open directly onto the skin surface. They are innervated by cholinergic nerve fibers … Heavy Sweating
Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment
Products Desvenlafaxine has been commercially available in the United States since 2008 in the form of sustained-release tablets (Pristiq). The drug is not currently registered or available in many countries or in the EU. Structure and properties Desvenlafaxine (C16H25NO2, Mr = 263.4 g/mol) is present in the drug as desvenlafaxine succinate and monohydrate, a white … Desvenlafaxine
Products St. John’s wort and corresponding preparations are commercially available in the form of teas, film-coated tablets, dragées, capsules, and tinctures, among others (e.g., Jarsin, Rebalance, Remotiv, Ceres, Hyperiforce, Hyperiplant, Offenware). Stem plant Common St. John’s wort L. is a perennial plant of the St. John’s wort family, native to Europe and also common in … St. John’s Wort Health Benefits
Products In many countries, tryptophan is commercially available as a dietary supplement, for example, in the form of capsules. Structure and properties L-tryptophan (C11H12N2O2, Mr = 204.2 g/mol) is an essential aromatic amino acid derived from indole. It exists as a white, crystalline or amorphous powder that is sparingly soluble in water. Effects Tryptophan (ATC … Tryptophan
Introduction Patients with depression have lower levels of certain neurotransmitters such as serotonin or norepinephrine in the brain than healthy people. According to current scientific knowledge, it is assumed that this lack of free neurotransmitters plays a decisive role in the development of depression. Antidepressants, i.e. drugs used to treat depression, intervene in precisely this … The role of serotonin neurotransmitters in depression
