It has been shown that isolated iridoids and coumarins of ash inhibit the formation of various mediators of inflammatory reactions (prostaglandins, leukotrienes). This inhibition could explain the anti-inflammatory and analgesic effects of the leaves and bark.
The laxative effect of manna is due to the mannitol it contains: the osmotically acting sugar increases the water content in the stool.
Ash: no side effects
Currently, there are no known side effects or interactions with other remedies or contraindications to taking ash leaves.