Therapy goals
- Improvement of the symptomatology
- Elimination of pathogens
Therapy recommendations
- Local antifungals (antifungal agents to be applied topically).
- Systemic therapy (indications: Failure of topical (“local”) therapy and in hyperkeratotic (“highly keratinizing”) tinea pedis).
- See also under “Further therapy“.
Further notes
- Meta-analysis: terbinafine scored as more effective in mycoses as oral therapy compared with azoles and griseofulvin, resulting in fewer side effects with a similar recurrence rate (disease recurrence).
- During oral antifungal therapy with terbinafine or griseofulvin, there was rarely transaminase elevation, anemia (anemia), lymphopenia (lack of lymphocytes in the blood), or neutropenia (decrease in neutrophil granulocytes in the blood) in liver-healthy children and adults; Laboratory values for aspartate aminotransferase (AST, ASAT; also called glutamate oxaloacetate transaminase (GOT)) and for parameters of anemia, lymphopenia, and neutropenia were similar to those before treatment.
