Benzene

Benzene is a chemical compound belonging to the group of aromatic hydrocarbons. It is an inhalation as well as a contact poison.

Benzene has a carcinogenic effect (cancer-causing). It is a component of gasoline, among other things.

Acute exposure to benzene may result in the following symptoms:

  • Loss of consciousness
  • Cephalgia (headache)
  • Intoxication
  • Mucous membrane irritations
  • Vertigo (dizziness)
  • Nausea (nausea / vomiting)
  • Nephropathies (kidney damage)
  • Oligomenorrhea – menstrual bleeding too infrequent (> 35 days and ≤ 90 days).
  • Pancytopenia (synonym: tricytopenia) – a deficiency in all three cell series (tricytopenia) of hematopoiesis, that is, when there is leukocytopenia (decrease in white blood cells), anemia (anemia), and thrombocytopenia (decrease in platelets)
  • Tachycardia – too fast pulse (> 100 beats/min).

The procedure

Material needed

  • EDTA blood
  • Spontaneous urine

Preparation of the patient

  • Not necessary

Disruptive factors

  • Not known

Standard values

Normal value – blood < 1.0 μg/l
Normal value – urine (metabolites) <15 mg/l (BAT 300 mg/l; phenol) <0.5 mg/l (muconic acid)

BAT value: biological agent tolerance value.

Indications

  • Suspected benzene exposure

Interpretation

Interpretation of lowered values

  • Not relevant to disease

Interpretation of elevated values

  • Benzene exposure