The medical history (history of the patient) represents an important component in the diagnosis of bone pain.
Family history
- Is there a history of frequent bone and/or joint disease in your family?
- Are there frequent tumor diseases?
Social history
- What is your profession?
Current medical history/systemic history (somatic and psychological complaints).
- How long has the pain been present? Have they changed in intensity? Have they become more severe?
- Where exactly is the pain localized? Does the pain radiate? Does the pain occur symmetrically?
- Does the pain occur more at rest or with movement?
- Is the pain more stabbing, burning or dull?
- Are there any other symptoms besides bone pain?
- Is there an acute restriction of movement?
- Has the pain occurred in conjunction with other changes or medication?
- Have you had an infection recently?
Vegetative anamnesis incl. nutritional anamnesis.
- Have you unintentionally lost body weight? Please tell us your body weight (in kg) and height (in cm).
- Do you exercise regularly every day?
Self history including medication history.
- Previous diseases (bone / joint diseases, tumor diseases (cancer), injuries).
- Operations
- Allergies
Medication history
- Antimony preparations
- Chelating agents (deferasirox, deferoxamine)
- Fluorides (fluorine)
- Hormones
- Aromatase inhibitors (anastrozole, testolactone).
- GNRH analogues (leuprorelin
- LHRH agonists (goserelin)
- STH (synonyms: somatotropic hormone (STH), somatotropin; e.g., growth hormone replacement therapy).
- Interferon (alpha interferon)
- Monoclonal antibodies (trastuzumab)
- Opioid receptor antagonists (naltrexone).
- Proton pump inhibitors (esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole).
- Retinoids – for therapy in psoriasis (psoriasis).
- Cytostatics
- Alkylants (temozolomide)
- Antimetabolites (methotrexate (MTX))