Cardiac Glycosides

Effects

  • Positive inotropic (hermuscular contractility).
  • Negative chronotropic (heart rate)
  • Negative dromotropic (excitation conduction)
  • Positive bathmotropic (stimulus threshold is lowered).

Indications

  • Heart failure
  • Arrhythmia

Agents

  • Digoxin (Digoxin Sandoz)
  • Digitoxin

Other active ingredients such as convallatoxin or proscillaridin are no longer commercially available today.

Stem plants

  • Adonis
  • Christmas rose
  • Foxglove, see under red foxglove
  • Lily of the Valley
  • Sea onion
  • Oleander
  • Strophanthus
  • Uzara root
  • Various animals, e.g. toads