A comprehensive clinical examination is the basis for selecting further diagnostic steps:
- General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further:
- Inspection (viewing).
- Skin and sclerae (white part of the eye) [leading symptom: exanthema (rash), especially macular (blotchy) or maculopapular (blotchy and with papules, i.e., vesicles)]
- Inspection (viewing).
- Dermatological examination [due topossible secondary diseases:
- Acute generalized exanthematous pustulosis (AGEP).
- Lyell syndrome (epidermolysis acuta toxica) as a maximum variant of drug exanthema (acute destruction of a large part of the epidermis (epidermis), which is life-threatening).
- Stevens-Johnson syndrome (SJS, synonyms: erythema exsudativum multiforme majus and dermatostomatitis Baader) – a skin disease resulting in high fever and exanthema; probably caused by mycoplasma or a consequence of drug allergy.
- Toxic epidermal necrolysis (TEN) – in which apoptosis mechanisms in the epidermis play a role]
Square brackets [ ] indicate possible pathological (pathological) physical findings.
