Facial Swelling: Or something else? Differential Diagnosis

Endocrine, nutritional, and metabolic diseases (E00-E90).

  • Cushing’s disease – group of disorders leading to hypercortisolism (hypercortisolism; excess of cortisol).
  • Myxedema in thyroid dysfunction (e.g., Hashimoto’s thyroiditis, hypothyroidism, Graves’ disease) – pasty (puffy; bloated) skin showing non-push-in, doughy edema (swelling) that is not position-dependent; in the facial area and peripherally

Skin and subcutaneous (L00-L99).

  • Rosacea erythematosa (copper rose; couperosis).
  • Rosacea fulminans – form of rosacea that develops acutely or peracutely within a few days or weeks with large, sometimes confluent (flowing together) nodes and numerous pustules (vesicles or pustules).
  • Urticaria – disease characterized by edematous efflorescences (wheals of the skin/mucous membrane).

Infectious and parasitic diseases (A00-B99).

  • Herpes zoster (shingles)
  • Herpes simplex labialis
  • Parotitis epidemica (mumps)
  • Trichinella – infectious disease caused by parasites of the species Trichinella (nematodes/filamentous worms).

Mouth, esophagus (food pipe), stomach and intestine (K00-K67; K90-K93).

  • Acute apical periodontitis (inflammation of the periodontium (periodontium) just below the root of the tooth; apical = “tooth rootward”; common in an avital tooth).
  • Bacterial parotitis (inflammation of the parotid gland).
  • Dental abscess – encapsulated collection of pus in the area of the tooth.
  • Dental cyst
  • Dentitio difficile (impeded eruption of a wisdom tooth).
  • Salivary stone (sialolith)
  • Root granulomas with fistula formation

Musculoskeletal system and connective tissue (M00-M99).

Neoplasms – tumor diseases (C00-D48).

  • Burkitt’s lymphoma – malignant (malignant) lymphoma, the formation of which is associated with the Epstein-Barr virus and is classified as B-cell non-Hodgkin’s lymphoma.
  • Nasopharyngeal carcinoma (nasopharyngeal cancer).
  • Neoplasm of the parotid gland (parotid gland).
  • Sarcoma in the region of the upper/lower jaw – malignant tumor originating from the mesenchymal tissue.

Psyche – nervous system (F00-F99; G00-G99).

  • Bruxism (teeth grinding) – unconscious, usually nocturnal but also daytime repetitive masticatory muscle activity that occurs through grinding or clenching of the teeth or Tension or pressing of the jaws occurs; typical consequences are morning muscular pain, hypertrophy of the musculus masseter (masseter muscle), abrasions (loss of tooth structure), wedge-shaped defects of the teeth, root resorptions (degradation of root cement or cement and dentin in the area of one or more tooth roots) and possibly also temporomandibular joint disorders.

Symptoms and abnormal clinical and laboratory findings not classified elsewhere (R00-R99).

  • Facial edema in:
    • Nephritis and nephrosis
    • Chronic terminal renal failure (kidney failure).
    • Thyroid dysfunction
    • Influence congestion

Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99)

  • Chronic terminal renal insufficiency (renal failure).
  • Nephritis – collective term for acute or chronic inflammatory diseases of the kidney.
  • Nephrosis – degenerative kidney disease.

Injuries, poisonings and other consequences of external causes (S00-T98).

  • Insect bites
  • Quincke’s edema (angioedema) – massive swelling of the subcutis (subcutaneous tissue) or submucosa (submucosal connective tissue), which usually affects the lips and eyelids, but may also affect the tongue or other organs
  • Injuries, unspecified (e.g., zygomatic bone fracture).

Other causes