The following are the most important diseases or complications that may be contributed to by focal segmental sclerosing glomerulonephritis: Genitourinary system (kidneys, urinary tract-genital organs) (N00-N99).
- Nephrotic syndrome – collective term for symptoms that occur in various diseases of the glomerulus (renal corpuscles); symptoms include: Proteinuria (excretion of protein in the urine) with protein loss greater than 1 g/m²/body surface area per day; hypoproteinemia, peripheral edema (water retention) due to serum hypalbuminemia of < 2.5 g/dL, hyperlipoproteinemia (dyslipidemia) with LDL elevation.
- Renal insufficiency (kidney weakness)/kidney failure with dialysis requirement or need for kidney transplantation.
