Gastrointestinal Bleeding: Prevention

To prevent gastrointestinal bleeding (gastrointestinal hemorrhage), attention must be paid to reducing individual risk factors.

In this regard, consider individual risk factors depending on the individual occurrence of each differential diagnosis.

Further notes

  • US seniors taking new oral anticoagulants (direct oral anticoagulants such as apixaban, dabigatran, or rivaroxaban; NOAK, nonvitamin K antagonist oral anticoagulants) were less likely to develop upper gastrointestinal bleeding if they were concomitantly prescribed a proton pump inhibitor (PPI; acid blocker). Note under PPI use: higher rates of Clostridium difficile infections, pneumonia, and osteoporotic fractures.