Estrogen Antagonists

Toremifene

Products Toremifene is commercially available in tablet form (Fareston). It was approved in many countries in 1996 and went off the market in 2012. Structure and properties Toremifene (C26H28ClNO, 405.96 g/mol) Effects Toremifene (ATC L02BA02) is antiestrogenic. Indications Local unresectable, locally recurrent, or metastatic postmenopausal breast carcinoma (breast cancer). Contraindications For complete precautions, see the … Toremifene

Fulvestrant

Products Fulvestrant is commercially available as a solution for injection (Faslodex, generic). It has been approved in many countries since 2004. Structure and properties Fulvestrant (C32H47F5O3S, Mr = 606.8 g/mol) exists as a white powder that is practically insoluble in water. Effects Fulvestrant (ATC L02BA03) has antiestrogenic properties. It is an antagonist at the estrogen … Fulvestrant