Peginterferon Beta-1A

Products Peginterferon beta-1a is commercially available as a solution for injection in a prefilled syringe (Plegridy). It was approved in many countries in 2015. Structure and properties Peginterferon beta-1a is a covalent conjugate of interferon beta-1a (Rebif) and methoxypolyethylene glycol with methylpropionaldehyde as a linker. Effects Peginterferon beta-1a (ATC L03AB13) has antiviral, antiproliferative, antitumor, and … Peginterferon Beta-1A

Peginterferon Alfa-2A

Products Peginterferon alfa-2a is commercially available as an injectable (Pegasys). It has been approved in many countries since 2002. Structure and properties Peginterferon alfa-2a is a covalent conjugate of the recombinant protein interferon alfa-2a and a branched monomethoxy polyethylene glycol (PEG). It has a molecular mass of approximately 60 kDa and is derived from by … Peginterferon Alfa-2A

Peginterferon Alfa-2B

Products Peginterferon alfa-2b was commercially available as an injectable (PegIntron). It had been approved in many countries since 2002. Structure and properties Peginterferon alfa-2b is a covalent conjugate composed of the recombinant protein interferon alfa-2b and a monomethoxy polyethylene glycol (PEG). It has a molecular weight of approximately 31 kDa. Peginterferon alfa-2b is obtained from … Peginterferon Alfa-2B

Interferon Alfa-2A

Products Interferon alfa-2a is commercially available as an injectable (Roferon-A). It has been approved in many countries since 1997. Structure and properties Interferon alfa-2a is a recombinant protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has a molecular mass of approximately 19 kDa. Effects Interferon alfa-2a (ATC L03AB04) … Interferon Alfa-2A

Interferon Alfa-2B

Products Interferon alfa-2b was commercially available as a drug for injection or infusion (Intron-A). It was approved in many countries as of 1998. In other countries, the drug remains available. Structure and properties Interferon alfa-2b is a recombinant, water-soluble protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has … Interferon Alfa-2B

Interferon Beta-1A

Products Interferon beta-1a is commercially available as a solution for injection (Avonex, Rebif). It has been approved in many countries since 1997. Structure and properties Interferon beta-1a is a recombinant protein biotechnologically derived from CHO cells. It consists of 166 amino acids, has the same amino acid sequence as natural interferon beta, and is glycosylated … Interferon Beta-1A

Interferon Beta-1B

Products Interferon beta-1b is commercially available as a powder and solvent for the preparation of a solution for injection (Betaferon). It has been approved in many countries since 1995. Structure and properties Interferon beta-1b is a recombinant protein of 165 amino acids with a molecular mass of approximately 18,500 Da. It is derived from an … Interferon Beta-1B

Interferon Gamma-1B

Products Interferon gamma is commercially available as a solution for injection (Imukin). It has been approved in many countries since 1997. Structure and properties Interferon gamma-1b is a protein consisting of 140 amino acids. It is obtained from a -strain by biotechnological methods. Effects Interferon gamma (ATC L03AB03) has antiviral, antiproliferative, antitumor, and immunostimulatory properties. … Interferon Gamma-1B

Ropeginterferon Alfa-2B

Products Ropeginterferon alfa-2b was approved as a solution for injection in many countries in 2020 (Besremi). Structure and properties Ropeginterferon alfa-2b is a recombinant interferon alfa-2b linked to a two-arm methoxypolyethylene glycol (mPEG). It has a molecular mass of approximately 60 kDa and is produced by biotechnological methods. Effects Ropeginterferon alfa-2b (ATC L03AB15) inhibits proliferation … Ropeginterferon Alfa-2B