Nucleoside Analogues

Aciclovir Lip Cream

Products Lip creams containing aciclovir have been approved in many countries since 1997 (Zovirax Lip Cream, generic). Structure and properties Aciclovir (C8H11N5O3, Mr = 225.2 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It mimics 2′-deoxyguanosine. Effects Aciclovir (ATC D06BB03) is antiviral against herpes simplex viruses. It is a prodrug … Aciclovir Lip Cream

Ribavirin

Products Ribavirin is commercially available in the form of film-coated tablets (Copegus). It has been approved in many countries since 1990. Structure and properties Ribavirin (C8H12N4O5, Mr = 244.2 g/mol) is a purine nucleoside analog. It exists as a white crystalline powder that is readily soluble in water. In cells, the drug is biotransformed to … Ribavirin