Uricosurics

Benzbromarone

Products Benzbromarone was withdrawn from the market in many countries in 2003 because of its hepatotoxicity. Desuric and other drugs are no longer available. It is still available in other countries. The withdrawal was not without controversy (Jansen, 2004). Structure and properties Benzobromarone (C17H12Br2O3, Mr = 424.1 g/mol) is a derivative of khellin. It exists … Benzbromarone

Probenecid

Products Probenecid is commercially available in tablet form (Santuril). Santuril has been approved in many countries since 2005. Structure and properties Probenecid (C13H19NO4S, Mr = 285.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Probenecid (ATC M04AB01) inhibits tubular reabsorption of uric acid and secretion of organic anions. It thus … Probenecid