Products Lotilaner was approved in the EU in 2017 and in the U.S. and many countries in 2018 in chewable tablet form for dogs and as chewable tablets for cats (Credelio). Structure and properties Lotilaners (C20H14Cl3F6N3O3S, Mr = 596.8 g/mol) belongs to the isoxazoline group and exists as a pure -enantiomer. Effects Lotilaner (ATCvet QP53BE04) … Lotilan
Products Fluralaner is commercially available as a veterinary drug in the form of chewable tablets and as a spot-on preparation (Bravecto). It was approved in many countries in 2015. Structure and properties Fluralaner (C22H17Cl2F6N3O3, Mr = 556.3 g/mol) is present in drugs as a racemate. It is a fluorinated isoxazoline-substituted benzamide. Effects Fluralaner (ATCvet QP53BX05) … Fluralaner
Products Sarolaner was approved in the EU in 2015 and in many countries in 2017 in the form of chewable tablets for dogs (Simparica). Structure and properties Sarolaner (C23H18Cl2F4N2O5S, Mr = 581.4 g/mol) belongs to the isoxazoline group. Effects Sarolaner (ATCvet QP53BX06) has antiparasitic properties against fleas, ticks, and mites. Indications For the treatment of … Sarolan
Products Afoxolaner is commercially available in the form of chewable tablets as a veterinary drug for dogs (NexGard). It was approved in many countries in 2015. Structure and properties Afoxolaner (C26H17ClF9N3O3, Mr = 625.9 g/mol) belongs to the isoxazoline group. Effects Afoxolaner (ATCvet QP53BX04) has insecticidal and acaricidal properties. Parasites ingest the active ingredient when … Afoxolan