Chondroitin Sulfate: Functions

Like the other glycosaminoglycans, chondroitin sulfates are negatively charged and highly hydrated. They attract positively charged sodium ions, which in turn induce water influx. Finally, chondroitin sulfate helps draw fluid into the proteoglycans and thus into the extracellular matrix (extracellular matrix, intercellular substance, ECM, ECM) of articular cartilage and synovium (synovial fluid). Chondroitin sulfate is … Chondroitin Sulfate: Functions