Nephrotic Syndrome: Diagnostic Tests

Obligatory medical device diagnostics.

  • Renal ultrasonography (ultrasound examination of the kidneys) [nephrotic syndrome: significantly enlarged kidneys, marked increase in parenchymechogenicity]
  • Renal biopsy (tissue sampling from the kidney) – for definitive diagnosis, treatment planning, prognosis assessmentNote:
    • Primarily not indicated in typical age of manifestation (childhood) and characteristic course with response to ex-juvantibus therapy (“clarification of the diagnosis from the cure”) with glucocorticoids.
    • Primarily indicated in patient age > 10 years, steroid resistance (resistance to glucocorticoids), nephritic syndrome or suspected systemic disease.
    • Renal biopsy is indicated only if it leads to therapeutic consequences.

Optional medical device diagnostics – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification.