Portal Hypertension: Prevention

To prevent portal hypertension (portal hypertension, portal vein hypertension), attention must be paid to reducing individual risk factors.

Behavioral risk factors

  • Consumption of stimulants
    • Alcohol (woman: > 40 g/day; man: > 60 g/day).

Primary prophylaxis

Primary prophylaxis aims to prevent initial variceal bleeding. The risk of this is approximately 30%. An increased risk of bleeding, which is considered an indication for primary prophylaxis, is said to occur when the so-called “red color signs” are detectable (stage III) and/or the variceal diameter is > 5 mm.

Primary prophylaxis is usually achieved by permanent use of non-selective beta-blockers, e.g. propranolol (see “Drug therapy“). The risk of bleeding can thus be reduced by approximately 50%.

If the risk of bleeding is high, ligation (see “Surgical Therapy” below) may also be indicated.