Obligatory medical device diagnostics.
- Renal ultrasonography (ultrasound of the kidneys; includes the urinary tract).
- [Acute glomerulonephritis: renal enlargement, cortical widening, and echogenicity increase of the renal cortex.
- Chronic glomerulonephritis: rather reduced kidneys, narrowed renal cortex and increased echogenicity and decreased corticomedullary differentiation.
- Nephrotic syndrome: significantly enlarged kidneys, marked increase in parenchymechogenicity]
Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics and mandatory medical device diagnostics – for differential diagnosis.
- Radiographs of thoracic organs and skeleton to exclude osteolysis (spatially circumscribed dissolution or degeneration of bone tissue).
- Computed tomography (CT) of the abdomen (abdominal CT) for further diagnosis.
- Renal biopsy (tissue sampling from the kidney); indicated only if it leads to therapeutic consequences!
- Large proteinuria (protein excretion of > 1 g/m 2KOF/d), persistent.
- Proteinuria associated with hematuria (blood or erythrocytes (red blood cells in urine) of glomerular origin and/or renal function impairment (glomerular filtration rate (GFR) < 80 ml/m 2 KOF/min)
- Indication of vascular systemic disease.
- Nephrotic syndrome (for definitive diagnosis, treatment planning, prognosis assessment), rapidly progressive glomerulonephritis, suspected malignant kidney disease