Quinisocaine

Products

Quinisocaine was commercially available in many countries as an ointment (isoquinol) since 1973. In 2013, distribution was discontinued.

Structure and properties

Quinisocaine (C₁₇H₂₄N₂O, M_r = 272.4 g/mol) is an isoquinoline derivative and is present in the drug as quinisocaine hydrochloride. It is classified as an amide-type local anesthetic.

Effects

Quinisocaine (ATC D04AB05) has local anesthetic, analgesic, and antipruritic properties. The effects are due to blockade of voltage-gated sodium channels.

Indications

For symptomatic treatment of itchy and painful skin conditions (e.g., insect bites, itching, sunburn, minor burns) and hemorrhoids.