Pathogenesis (development of disease)
In radiation enteritis, the application of radiation causes acute inflammation of the intestinal mucosa. This can limit the absorption surface for nutrients (macro- and micronutrients). In addition, the goblet cells (mucus-producing cells) empty, and mucus is discharged with the stool. Late damage from radiation therapy occurs due to sclerosis (hardening) of the intestinal vessels.
Etiology (causes)
X-rays
- Large-volume radiotherapy (radiotherapy) of the abdomen (abdominal cavity) for tumor disease; higher risk when combined with chemotherapy
