Reactive Arthritis: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate reactive arthritis/Reiter’s disease:

Reiter’s triad

  • Acute arthritis* (joint inflammation) – often asymmetric mono- or oligoarthritis (one or fewer than five joints; very rarely polyarthritis); aseptic (“germ-free”); localization:
  • Conjunctivitis (inflammation of the conjunctiva)
  • Urethritis (inflammation of the urethra)

* If necessary, also only mild arthralgia (joint pain).

Leading symptoms

  • Dactylitis (finger/toe inflammation), especially of the forefeet; asymmetric spread.
  • Enthesitis – inflammation of tendon/tendon attachments; often in the Achilles tendon region.
  • Erythema nodosum (synonyms: nodular erysipelas, dermatitis contusiformis, erythema contusiforme; plural: erythemata nodosa) – granulomatous inflammation of the subcutis (subcutaneous fat tissue), also known as panniculitis, and a painful nodule (red to blue-red color; later brownish). The overlying skin is reddened. Localization: both lower leg extensor sides, on the knee and ankle joints; less frequently on the arms or buttocks.
  • Aphthous changes in the oral mucosa.
  • Keratoderma blenorrhagicum – chronic recurrent pustulosis/hyperkeratotic changes on the palms of the hands and soles of the feet.
  • Balanitis circinata (acorn inflammation)

Often the various symptoms occur over the course of weeks or months and not at the same time. The infection can also proceed asymptomatically (without symptoms).