Reserpine

Products

Reserpine was commercially available in many countries in the form of dragées as a fixed combination with dihydroergocristin and clopamide (Brinerdin, off label).

Structure and properties

Reserpine (C₃₃H₄₀N₂O₉, M_r = 609 g/mol) exists as a crystalline powder or as small, white to faint yellow crystals that slowly darken under the influence of light. The substance is practically insoluble in water.

Effects

Reserpine (ATC C02AA02) has sympatholytic, antihypertensive, vasodilator, and central sedative properties.

Stem

Rauvolfia.

Indications

For the treatment of hypertension.