Products Minoxidil is commercially available as a solution and in some countries also as a foam (Regaine, generics, USA: Rogaine). It has been approved in many countries since 1987. The brand name plays on the English verb , which translates as to recover or get back. This article refers to external use. Tablets also exist … Minoxidil
Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects
Products Most sartans are commercially available as tablets or film-coated tablets. Losartan was the first agent approved in many countries in 1994 (Cosaar, USA: 1995, Cozaar). Sartans are often combined with hydrochlorothiazide fix. The name of the drug group is derived from the suffix -sartan of the active ingredients. The drugs are also called angiotensin … Sartans
Products Beta-blockers are available in many countries in the form of tablets, film-coated tablets, sustained-release tablets, as capsules, solution, eye drops, and as injection and infusion solutions. Propranolol (Inderal) was the first representative of this group to appear on the market in the mid-1960s. Today, the most important active ingredients include atenolol, bisoprolol, metoprolol and … Beta Blocker Effects and Side Effects
Products Moxonidine is commercially available in tablet form (Physiotens). It has been approved in many countries since 1993. Structure and properties Moxonidine (C9H12ClN5O, Mr = 241.7 g/mol) exists as a white powder that is very sparingly soluble in water. It is an imidazoline derivative structurally related to clonidine. Effects Moxonidine (ATC C02AC05) has central antihypertensive … Moxonidine
Products Reserpine was commercially available in many countries in the form of dragées as a fixed combination with dihydroergocristin and clopamide (Brinerdin, off label). Structure and properties Reserpine (C33H40N2O9, Mr = 609 g/mol) exists as a crystalline powder or as small, white to faint yellow crystals that slowly darken under the influence of light. The … Reserpine
Products Methyldopa is commercially available in the form of film-coated tablets (Aldomet). It has been approved in many countries since 1962. Structure and properties Methyldopa (C10H13NO4, Mr = 211.2 g/mol) is an α-methylated derivative of the amino acid and dopamine precursor levodopa. It is present in drugs as anhydrous methyldopa (Methyldopum anhydricum) or as methyldopa … Methyldopa
Products Nitroprusside is available as an infusion preparation in some countries (eg, Nitropress). It was approved in many countries in 2019. Nitroprusside is an old drug, developed in the 19th century and first used medically in the 1920s. Structure and properties Nitroprusside (Na2(Fe(CN)5NO) – 2H2O), Mr = 298.0 g/mol) is present in the drug as … Nitroprusside
Products Guanethidine is no longer on the market in many countries and many others. Ismelin tablets (Ciba-Geigy) are no longer available. Structure and properties Guanethidine (C10H22N4, Mr = 198.3 g/mol) is present in drugs as guanethidine monosulfate, a white crystalline powder that is highly soluble in water. It is a guanidine derivative. Effects Guanethidine (ATC … Guanethidine
Products Alpha blockers are available in many countries in the form of tablets, sustained-release tablets, capsules, and sustained-release capsules. The most commonly prescribed today is tamsulosin (Pradif T, generic). Alpha blocker is short for alpha1-adrenoreceptor antagonist. Structure and properties The first alpha blockers-alfuzosin, doxazosin, and terazosin-were developed as derivatives of quinazoline: Effects Alpha blockers (ATC … Alpha Blocker
