Rickets (Osteomalacia): Diagnostic Tests

Obligatory medical device diagnostics.

  • Conventional radiographs of affected bones – show in the presence of rickets or osteomalacia:
    • Calcified skeleton with fused bone structure (classic milk glass structure of the bones).
    • Characteristic Loosersche remodeling zones (bilateral and symmetrically arranged, ligamentous, low-calcification zones; in typical localizations are lateral scapular rim (lateral scapula), proximal humerus (humerus), upper ribs, pubic bones, femoral neck, and medially on proximal femur (thigh bone)
    • Possibly fish vertebrae with compaction in the top and bottom plate area of the vertebral bodies.
    • Possibly pseudofractures (creeping fatigue fractures) and fissures / insufficiency fractures
  • If necessary, skeletal scintigraphy – search for areas with increased bone metabolism (→ finding fracture areas (bone fractures; esp. rib fractures) in generalized bone pain).
  • If necessary, magnetic resonance imaging (MRI) and computed tomography (CT) – for clarification.
    • The extent of a fracture (stability?; age?).
    • Of underlying metastases (daughter tumors)/tumors.
  • If necessary, 18F-fluorodeoxyglucose positron emission tomography and octreotide scintigraphy – to search for tumors.
  • Dual X-ray absorptiometry (DXA, DEXA; dual X-ray absorptiometry; radiographic method)/bone densitometry – to obtain baseline findings and to monitor progress.