Xanthine: Function & Diseases

Xanthine is formed as an intermediate in the breakdown of purine nucleotides to uric acid. Thus, it represents a central molecule in the context of nucleic acid metabolism. When xanthine degradation is disturbed, so-called xanthinuria occurs. What is xanthine? Xanthine represents an intermediate product in purine degradation in the organism. The most important starting compounds … Xanthine: Function & Diseases

Guanine: Function & Diseases

Guanine is an important nitrogen base and has a central role in nucleic acid metabolism in the organism. It can be synthesized in the body from amino acids. However, due to the high energy expenditure of this reaction, its recovery often occurs via the salvage pathway. What is guanine? Guanine is one of the five … Guanine: Function & Diseases

Guanosine: Function & Diseases

Guanosine is the nucleoside of the purine base guanine and is formed by the addition of the simple sugar ribose. If deoxyribose, rather than ribose, is attached, it is deoxyguanosine. Guanosine is a component of the helices and double helices of RNA. The analogue deoxyguanosine is part of DNA. Guanosine, as a guanosine triphosphate (GTP) … Guanosine: Function & Diseases

Cobalamins: Function & Diseases

Cobalamins represent chemical compounds that belong to the vitamin B12 group. They are found in all organisms. Their synthesis occurs only by bacteria. What are cobalamins? Cobalamins are a group of chemical compounds with the same basic structure that belong to the vitamin B12 complex. They are a complex compound with cobalt as the central … Cobalamins: Function & Diseases

Ribothymidine: Function & Diseases

Ribothymidine is a nucleoside that is a building block of tRNA and rRNA. As such, it plays an important role in numerous metabolic processes. What is ribothymidine? Ribothymidine is also known as 5-methyluridine. It is a nucleoside. Nucleosides are single molecules of tRNA and rRNA that occur within cells. The tRNA or transfer DNA is … Ribothymidine: Function & Diseases

Thymine: Function & Diseases

Thymine is one of the four nucleic bases that make up DNA strands, the seat of genetic information. The complementary base in the double helix is always adenine. Chemically, it is a heterocyclic aromatic compound with a pyrimidine backbone. In addition to serving as a nucleic base in DNA to encode the amino acid sequence … Thymine: Function & Diseases