Anastrozole: Effects, Applications, Side Effects

How anastrozole works Anastrozole is a so-called reversible aromatase inhibitor. The active ingredient blocks the enzyme aromatase and thus prevents the formation of female sex hormones (estrogen synthesis). During the development of the female sex organs in puberty, the body selectively secretes estrogens to stimulate the tissues concerned to grow. After the end of puberty, … Anastrozole: Effects, Applications, Side Effects

Anastrozole

Products Anastrozole is commercially available in the form of film-coated tablets (Arimidex, generic). It has been approved in many countries since 1996. Structure and properties Anastrozole (C17H19N5, Mr = 293.4 g/mol) exists as a white powder that is very sparingly soluble in water. It is a triazole derivative with a non-steroidal structure. Effects Anastrozole (ATC … Anastrozole

Letrozole

Products Letrozole is commercially available in the form of film-coated tablets (Femara, generic). It has been approved in many countries since 1997. Structure and properties Letrozole (C17H11N5, Mr = 285.3 g/mol) is a nonsteroidal aromatase inhibitor. It exists as a white to yellowish crystalline powder that is nearly odorless and virtually insoluble in water. Letrozole … Letrozole

Doping in Competitive Sports

Products Doping agents include approved drugs, legal and illegal intoxicants, experimental agents, and illegally manufactured and trafficked substances. Doping includes non-drug doping methods, such as blood doping, in addition to drugs. Effects Doping agents differ in their pharmacological activities. Stimulants, for example, stimulate and thus increase alertness and aggressiveness for competition. In contrast, beta-blockers provide … Doping in Competitive Sports

Antiestrogen: Effects, Uses & Risks

Antiestrogens are a group of drugs that are used exclusively in women to treat breast cancer. They are injectable solutions that remain in the body for a long period of time and can treat, but not completely eliminate, breast cancer there. What is antiestrogen? Antiestrogens are a group of medications used exclusively in women to … Antiestrogen: Effects, Uses & Risks

Aromatase Inhibitors

Products Aromatase inhibitors are commercially available in the form of film-coated tablets and coated tablets. The first third-generation agent to be approved in many countries was anastrozole in 1996 (Arimidex, USA 1995). Other drugs are available today. The active ingredients available today all belong to the third generation. Earlier agents such as aminoglutethimide and formestane … Aromatase Inhibitors

Anastrozole: Effects, Uses & Risks

Anastrozole inhibits the estrogen-dependent growth of breast cancer. The drug is used primarily in postmenopausal women and in men as part of endocrine therapy (antihormone therapy) for estrogen-sensitive breast cancer. What is anastrozole? Anastrozole inhibits the estrogen-dependent growth of breast cancer. As a benzyltriazole derivative, anastrozole belongs to the non-steroidal aromatase inhibitor drug class. It … Anastrozole: Effects, Uses & Risks