Products Meldonium is on the market mainly in Eastern European countries and states of the former Soviet Union in the form of capsules and as an injectable, for example in Russia, Belarus, Ukraine, and Latvia (Mildronate). However, it is not registered in many countries, in the EU and in the USA. Meldonium was developed in … Meldonium
Products In many countries, no drugs containing trimetazidine are commercially available. In other countries, film-coated tablets of modified release and dropper solutions are available (e.g., Vastarel), among others. Structure and properties Trimetazidine (C14H22N2O3, Mr = 266.3 g/mol) is a piperazine derivative. It is present in the drug as trimetazidine dihydrochloride. Effects Trimetazidine (ATC C01EB15) has … Trimetazidine
Products Verapamil is commercially available in the form of film-coated tablets and sustained-release tablets (Isoptin, generic). It has been approved in many countries since 1964. Verapamil is also combined fixed with trandolapril (Tarka). Structure and properties Verapamil (C27H38N2O4, Mr = 454.60 g/mol) is a racemate consisting of the – and -enantiomer. It is an analog … Verapamil: Drug Effects, Side Effects, Dosage and Uses
Products Amlodipine is commercially available in tablet form (Norvasc, generic). It has been approved in many countries since 1990. Amlodipine is also combined fixed with the following agents: Aliskiren, atorvastatin, perindopril, telmisartan, valsartan, olmesartan, hydrochlorothiazide, and indapamide. Structure and properties Amlodipine (C20H25ClN2O5, Mr = 408.9 g/mol) has a chiral center and is a racemate. It … Amlodipine (Norvasc)
Products Ranolazine is commercially available in the form of sustained-release tablets (Ranexa). It was approved in the United States as early as 2006, in the EU in July 2008, and in many countries in April 2010. Structure and properties Ranolazine or ()–(2, 6-dimethylphenyl)-4(2-hydroxy-3-(2-methoxyphenoxy)-propyl)-1-piperazine acetamide (C24H33N3O4, Mr = 427.54 g/mol) is a piperazine derivative and a … Ranolazine
Products Mibefradil (Posicor tablets) was launched in many countries in 1996 and withdrawn from the market in 1998 because of potential interactions. It is no longer commercially available. Structure and properties Mibefradil (C29H38FN3O3, Mr = 495.6 g/mol) is a benzimidazole and a tetralol derivative. It is present in drugs as mibefradildihydrochloride. Effects Mibefradil (ATC C08CX01) … Mibefradil
