Dihydroartemisinin

Products No drugs containing dihydroartemisinin are currently approved in many countries. However, the prodrug artemether (Riamet, with lumefantrine), which is metabolized in the body to dihydroartemisinin, is available. It is also combined fixed with piperaquine; see Piperaquine and Dihydroartemisinin. Structure and properties Dihydroartemisinin (C15H24O5, Mr = 284.3 g/mol) is derived from artemisinin from annual mugwort … Dihydroartemisinin

Amodiaquine: Effects, Uses & Risks

Amodiaquine is an active ingredient used to treat malaria. It is used as a monotherapy and combination preparation, particularly against malaria tropica, which is caused by the unicellular parasite Plasmodium falciparum. What is amodiaquine? Amodiaquine is an active ingredient used to treat malaria. Amodiaquine is an aromatic hydrocarbon. It belongs to the 4-amino-choline group and … Amodiaquine: Effects, Uses & Risks

Artemisinin: Effects, Uses & Risks

The secondary plant pigment artemisinin from the flowers and leaves of the annual mugwort is used to treat malaria. The drug is used primarily in areas where other antimalarial drugs are ineffective against multidrug-resistant pathogens. The remedy is already mentioned in traditional Chinese medicine, which is thousands of years old. What is artemisinin? The secondary … Artemisinin: Effects, Uses & Risks

Malaria Causes and Treatment

Symptoms Malaria (Italian, “bad air”) manifests itself in the following symptoms, which usually appear a few weeks after transmission. The incubation period ranges from a few days to several years: High fever, sometimes with rhythmic attacks of fever, every second or third day. However, the fever may also occur irregularly. Chills, profuse sweating. Headache, muscle … Malaria Causes and Treatment

Antimalarials

Effects Antiparasitic against plasmodia. Indications Malaria Malaria prophylaxis Also for the treatment of rheumatic diseases, lupus erythematosus. Off-label: some antimalarials such as quinine and chloroquine are used off-label to treat calf cramps. Active ingredients Aminoquinolines: Amodiaquine Chloroquine (Nivaquine, out of commerce). Hydroxychloroquine (Plaquenil) Mepacrine Pamaquin Piperaquine Primaquine Tafenoquin (crinoline) Biguanides: Proguanil (Malarone + Atovaquone). Cycloguanilembonate … Antimalarials

Artesunate

Products No drugs containing artesunate are currently approved in many countries. Structure and properties Artesunate (C19H28O8, Mr = 384.4 g/mol) is a succinyl derivative and a prodrug of dihydroartemisinin. It is derived from artemisinin from annual mugwort (, qing hao), a medicinal plant used in traditional Chinese medicine. Effects Artesunate (ATC P01BE03) has antiparasitic properties … Artesunate

Artesunate: Effects, Usage & Risks

Artesunate is an active ingredient used to treat malaria. The tropical infectious disease is caused by pathogens of the genus Plasmodium and claims 1 million lives worldwide each year. As studies show, the active ingredient could also be used in the future to treat malignant – that is, malignant – tumors. What is artesunate? Artesunate … Artesunate: Effects, Usage & Risks