bone marrow transplant

Bone Marrow Transplantation: Treatment, Effects & Risks

Bone marrow transplantation involves the transfer of bone marrow, and therefore stem cells, to restore regular hematopoiesis. Bone marrow transplantation is generally indicated when the hematopoietic cell system has been severely compromised as a result of tumor disease or previous therapy (especially high-dose chemotherapy). What is bone marrow transplantation? Bone marrow transplantation involves the transfer … Bone Marrow Transplantation: Treatment, Effects & Risks

Saving Leukemia Patients with a Stem Cell Donation

Every 16 minutes, a person in Germany receives a diagnosis of leukemia. If chemotherapy or radiation is unsuccessful, a stem cell or bone marrow transplant is often the last chance for patients. For about one third of patients, a donation from the family is an option, but often an outside donor is needed, who can … Saving Leukemia Patients with a Stem Cell Donation

Bruton-Gitlin Syndrome: Causes, Symptoms & Treatment

Bruton-Gitlin syndrome is an immunodeficiency that deprives the B cells of the immune system of the ability to produce and secrete antibodies and can therefore be classified as an antibody deficiency syndrome. The disease, which is usually mild, is inherited in an X-linked recessive manner and is based on a defect in the BTK gene. … Bruton-Gitlin Syndrome: Causes, Symptoms & Treatment

Stem Cell Transplantation: Treatment, Effects & Risks

In a stem cell transplant, stem cells are obtained from peripheral blood and transfused into a recipient to regenerate the hematopoietic system. For many leukemia sufferers in particular, stem cell transplantation represents the only chance for a cure, but it is also becoming increasingly important in the treatment of severe inborn errors of metabolism and … Stem Cell Transplantation: Treatment, Effects & Risks

Mucopolysaccharidosis: Causes, Symptoms & Treatment

Mucopolysaccharidosis is a collective term for lysosomal storage diseases based on the storage of glycosaminoglycans. All diseases develop similar symptoms and courses. The severity of the syndromes varies widely. What is mucopolysaccharidosis? There is no such thing as mucopolysaccharidosis as a single disease. The term mucopolysaccharidosis represents a collective term for a variety of storage … Mucopolysaccharidosis: Causes, Symptoms & Treatment

Peroxisomal Disease: Causes, Symptoms & Treatment

The term peroxisomal disease is used to describe genetic defects that affect the formation of peroxisomes, the transport of proteins or enzymes across the peroxisomal membrane, or the function of peroxisomal enzymes themselves. A great many oxygen-dependent systemically active reactions occur in the peroxisomes. Disruption of metabolic processes, for example, can have serious effects on … Peroxisomal Disease: Causes, Symptoms & Treatment

Graft-versus-host Reaction: Causes, Symptoms & Treatment

Graft-versus-host reaction is an immunologic complication that can lead to graft rejection in allogeneic transplantation. Meanwhile, the reaction can be controlled by the prophylactic administration of immunosuppressants. Nevertheless, a mortality rate of ten percent still applies today. What is the graft-versus-host reaction? In a transplant, organic material is transplanted from a donor into a recipient. … Graft-versus-host Reaction: Causes, Symptoms & Treatment

Bone Marrow

Synonyms Medulla ossium Definition The bone marrow fills the interior of the bone and is the main site of blood formation in humans. Many diseases are caused by an imbalance in cell formation in the bone marrow. For example, leukemias and anemias (anemia), which can occur in the context of many basic diseases. Anatomy The … Bone Marrow

Diseases of the bone marrow | Bone Marrow

Diseases of the bone marrow An important disease of the bone marrow is leukemia. There are different forms of leukemia, depending on whether it develops quickly or slowly and which cell rows are affected. However, they often have one thing in common: a patient with leukemia can therefore be conspicuous by paleness (anemia), increased bruising … Diseases of the bone marrow | Bone Marrow

The bone marrow in therapy | Bone Marrow

The bone marrow in therapy It can be therapeutically very valuable to transplant certain blood cells, i.e. to give them to a human being. These blood cells are stem cells that have the ability to develop into numerous different blood cells. Such a transplant can be performed with cells from peripheral blood, i.e. similar to … The bone marrow in therapy | Bone Marrow

Fanconi Anemia: Causes, Symptoms & Treatment

The hereditary disease Fanconi anemia occurs in very rare cases. Under appropriate circumstances, the disease can be cured. What is Fanconi anemia? Fanconi anemia is the medical term for an inherited form of anemia (anemia). In the context of this very rare hereditary disease, the production of red and white blood cells is impaired in … Fanconi Anemia: Causes, Symptoms & Treatment

Farber Disease: Causes, Symptoms & Treatment

Farber disease is a very rare metabolic disorder that causes severe physical impairment and leads to death. Newborns only develop the disease if both parents are carriers of the same defective gene. Since there is no specific therapy for the disease, it is currently incurable. What is Farber disease? Farber disease is an incurable metabolic … Farber Disease: Causes, Symptoms & Treatment