Cisplatin: Effects, Areas of Application, Side Effects

How cisplatin works Cisplatin is an inorganic platinum-containing heavy metal compound. It is a so-called cytostatic drug: It inhibits DNA synthesis in cells by senselessly cross-linking the DNA strands. This means that the DNA information cannot be read or can only be read incorrectly. Cell division is thus inhibited – the cell perishes. Absorption, degradation … Cisplatin: Effects, Areas of Application, Side Effects

Percutaneous Ethanol Injection Therapy (Liver): Treatment, Effects & Risks

Percutaneous ethanol injection therapy (liver) is a therapeutic method to treat carcinoma of the liver cells. Percutaneous ethanol injection therapy (liver) is usually abbreviated as PEI therapy. In the procedure, ethanol is delivered by injection, causing localized tissue death. What is percutaneous ethanol injection therapy (liver)? Percutaneous ethanol injection therapy (liver) should not be confused … Percutaneous Ethanol Injection Therapy (Liver): Treatment, Effects & Risks

Carboplatin

Products Carboplatin is commercially available as an infusion solution (paraplatin, generic). It has been approved in many countries since 1986. Structure and properties Carboplatin (C6H12N2O4Pt, Mr = 371.3 g/mol) is a platinum compound. It exists as a colorless crystalline powder that is sparingly soluble in water. Carboplatin is structurally related to cisplatin, the first platinum … Carboplatin

Necitumumab

Products Necitumumab was approved as an infusion solution in the United States in 2015 and in the EU in 2016 (Portrazza). Necitumumab has not yet been registered in many countries. Structure and properties Necitumumab is a recombinant human IgG1 monoclonal antibody. It is produced by biotechnological methods. Effects Necitumumab has antitumor, antiproliferative, and antiangiogenic properties. … Necitumumab

Cisplatin: Effects, Uses & Risks

The active substance cisplatin belongs to the cytostatic drugs. It is used to treat malignant cancers. What is cisplatin? Cisplatin (cis-diammine dichloridoplatin) is a cytostatic drug that inhibits the growth of cancer cells. The drug forms an inorganic platinum-containing heavy metal compound and has a complex-bound platinum atom. Cisplatin is in the form of orange-yellow … Cisplatin: Effects, Uses & Risks

Magnesium Deficiency

Symptoms Possible symptoms of clinically manifest magnesium deficiency include: Neuromuscular symptoms such as a tremor, muscle spasms, fasciculations (involuntary muscle movements), seizures Central disorders: Apathy, fatigue, dizziness, delirium, coma. Cardiovascular disorders: ECG changes, cardiac arrhythmias, palpable heartbeats, hypertension. Osteoporosis, Altered glucose homeostasis. Magnesium deficiency is often accompanied by calcium and potassium deficiency. However, many patients … Magnesium Deficiency

Cisplatin

Products Cisplatin is available as an infusion concentrate. Several generic products are available in many countries. Platinol is out of commerce. Structure and properties Cisplatin (PtCl2(NH3)2, Mr = 300.1 g/mol) or -diammine dichloroplatinum(II) exists as a yellow powder or as orange-yellow crystals and is sparingly soluble in water. It is an inorganic heavy metal complex … Cisplatin

Oxaliplatin

Products Oxaliplatin is commercially available as an infusion concentrate (Eloxatin, generic). It was approved in many countries in 2000 as a third platinum compound for cancer therapy. Structure and properties Oxaliplatin (C8H14N2O4Pt, Mr = 397.3 g/mol) is a platinum compound. It exists as a white crystalline powder and is sparingly soluble in water. Effects Oxaliplatin … Oxaliplatin

Lung Cancer Causes and Treatment

Symptoms Lung cancer may initially be asymptomatic. It is often discovered only when it is no longer curable. Possible typical symptoms include a chronic cough, coughing up blood, difficulty breathing, recurrent colds, chest pain, and weakness, fatigue, lack of appetite, and weight loss. If spread further, additional symptoms include hoarseness, noises when breathing, and difficulty … Lung Cancer Causes and Treatment

Lamivudine: Effects, Uses & Risks

The active substance lamivudine is used to treat the immunodeficiency disease AIDS and hepatitis B infections. It belongs to the antiviral drug group. What is HIV infection? Lamivudine is a nucleoside reverse transcriptase inhibitor (NRTI) that forms a chemical analog of cytidine, which is one of the nucleosides. The drug is used to treat HIV-1 … Lamivudine: Effects, Uses & Risks