cushing's disease

Cushing’s Disease: Definition, Symptoms, Therapy

Brief overview Symptoms: Altered fat distribution, truncal obesity, “moon face”, on the other hand relatively thin limbs, muscle weakness, bone atrophy, increased susceptibility to infections, in women: impure skin, signs of masculinization (e.g. strong facial hair) Course of disease and prognosis: Depends on cause, treatability and duration of the disease; often successful treatment possible, risk … Cushing’s Disease: Definition, Symptoms, Therapy

Fibrous Dysplasia: Causes, Symptoms & Treatment

Fibrous dysplasia, although a rare condition, is the most common malformation of the bone system in childhood and adolescence. Prognosis and course are generally favorable in fibrous dysplasia resulting from mutative changes. What is fibrous dysplasia? Fibrous dysplasia is a rare benign disorder or lesion of the human skeleton that is associated with bone malformations … Fibrous Dysplasia: Causes, Symptoms & Treatment

Pasireotide

Products Pasireotide is commercially available as an injectable (Signifor, Signifor LAR). It was approved in the EU and many countries in 2012. Structure and properties Pasireotide (C59H67N9O9, Mr = 1046.2 g/mol) is present in the drug as pasireotide diaspartate or as pasireotide pamoate. It is a cyclohexapeptide and an analog of the hormone somatostatin. Somatostatin … Pasireotide

Carcinoid Syndrome

Symptoms The main symptoms are diarrhea with watery stools, cramps in the lower abdomen, and flushing, which is seizure-like severe facial redness or purplishness, although the neck or legs may also be affected. The untreated or undiagnosed disease can lead to valvular heart defect, telangiectasias, and pellagra (vitamin B2 deficiency). Causes Carcinoid syndrome is based … Carcinoid Syndrome

Cushings Disease: Causes, Symptoms & Treatment

Cushing’s disease represents a condition in which the body experiences hypercortisolism, which is an overproduction of cortisol. This imbalance is caused by a pituitary adenoma (tumor of the pituitary gland), which in turn results in increased production and secretion of ACTH. What is Cushing’s disease? Named after the American neurologist Harvey Williams Cushing, Cushing’s disease … Cushings Disease: Causes, Symptoms & Treatment

What happens when the Cushing’s threshold is crossed? | Cushing’s threshold

What happens when the Cushing’s threshold is crossed? If the Cushing threshold is exceeded once, no direct consequences are usually to be expected. Since Cushing’s syndrome is a chronic disease, it is unlikely that a single dose overdose will cause symptoms. A long-term exceeding of the Cushing’s threshold becomes problematic. This greatly increases the probability … What happens when the Cushing’s threshold is crossed? | Cushing’s threshold

Cushing’s Syndrome

Synonyms in a broader sense English: Cushing’s syndrome Hypercortisolism Cushing’s disease Endocrine and exocrine Cushing’s syndrome Definition In Cushing’s syndrome (Cushing’s disease) there is too much cortisol in the body. Cortisol is a hormone that is produced by the body itself, but is also used as a drug, for example to suppress inflammatory reactions. Overactivity … Cushing’s Syndrome

What is the Cushing’s threshold? | Cushing’s Syndrome

What is the Cushing’s threshold? Cushing’s syndrome describes a group of symptoms caused by an excessive level of cortisone in the blood. The symptoms are, for example, the development of diabetes mellitus, or a full moon face, trunk obesity, stretch marks on the stomach or osteoporosis. The most common reason for the occurrence of Cushing’s … What is the Cushing’s threshold? | Cushing’s Syndrome

Diagnosis | Cushing’s Syndrome

Diagnosis If a Cushing’s syndrome is suspected, it must first be clarified whether the symptoms are caused by a drug-based cortisol therapy or not. If the patient takes cortisone regularly, an ectopic Cushing’s syndrome is most likely present. Special examinations are carried out if the patient is not treated with cortisol but has typical symptoms … Diagnosis | Cushing’s Syndrome

Therapy | Cushing’s Syndrome

Therapy If cortisol is given as a drug, a reduction of the dose may be considered to reduce the symptoms of the cushing-. syndrome. If the disease is based on a hormone-producing tumour, surgery should be performed for the causal treatment of Cushing’s syndrome: The adrenal gland or pituitary tumour is removed surgically. The hormones … Therapy | Cushing’s Syndrome

What is the life expectancy for Cushing’s syndrome? | Cushing’s Syndrome

What is the life expectancy for Cushing’s syndrome? Life expectancy in Cushing’s syndrome depends on the cause of the Cushing’s syndrome. Cushing’s syndrome can be caused by long-term use of excessive amounts of glucocorticoids, which have the same effect as cortisone in the body. In this case Cushing’s syndrome is curable by discontinuing the medication … What is the life expectancy for Cushing’s syndrome? | Cushing’s Syndrome

Cushing’s syndrome in horses | Cushing’s Syndrome

Cushing’s syndrome in horses Cushing’s syndrome is also a comparatively common metabolic disorder in horses. The excess of the hormone cortisone has similar effects on the metabolic processes as in humans or many other animals. Metabolic processes involved in fertility, sugar and fat metabolism, the immune system and many other body processes are also disturbed. … Cushing’s syndrome in horses | Cushing’s Syndrome