Dexmedetomidine: Effects, dosage

How does dexmedetomidine work? Dexmedetomidine inhibits the release of the nerve messenger noradrenaline in a specific brain region: the locus caeruleus. This structure of the brain is particularly rich in nerve cells that communicate via norepinephrine and are involved in controlling orientation as well as attention. Less norepinephrine due to dexmedetomidine subsequently means less messenger … Dexmedetomidine: Effects, dosage

Dexmedetomidine

Products Dexmedetomidine is commercially available as a concentrate for the preparation of an infusion solution (Dexdor). It was approved in many countries in 2012. Structure and properties Dexmedetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative and the -enantiomer of medetomidine. It is structurally closely related to detomidine and is present in drugs as … Dexmedetomidine

Medetomidine

Products Medetomidine is commercially available as an injection solution for animals. It has been approved in many countries since 1990. Structure and properties Medetomidine (C13H16N2, Mr = 200.3 g/mol) is an imidazole derivative that is structurally closely related to detomidine. Medetomidine is a racemate; the pure -enantiomer dexmedetomidine is also used. Effects Medetomidine (ATCvet QN05CM91) … Medetomidine